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应激状态下危重症患儿胰岛功能的探讨 被引量:7

Study on the pancreatic islets functions of the serious sick children on stress condition
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摘要 目的研究30例危重症患儿应激状态下血清胰岛素、C肽、血糖之间的关系,探讨胰岛功能应激和贮备代偿能力。方法应用放射免疫法对30例危重症患儿和30例对照组在静脉滴注葡萄糖0.5g/kg0.5h滴完状态下,在0min、30min时相分别测胰岛素、C肽、血糖。结果两时相观察组血糖值与对照组相比较均有显著差异(P<0.001)。空腹C肽(FCP)、胰岛素(FINS)观察组显著高于对照组(P<0.001)。空腹β细胞功能指数(FBCI),观察组与对照组比较无明显差异(P>0.05)。峰值β细胞功能指数(PBCI),对照组显著高于观察组(P<0.001)。峰值C肽与FCP之比(PCP/FCP)、峰值胰岛素与FINS之比(PINS/FINS),对照组显著高于观察组(P<0.001)。结论危重患儿胰岛功能的贮备代偿不足,并且存在胰岛素抵抗现象。二者是危重患儿糖代谢紊乱的原因。
出处 《小儿急救医学》 2005年第3期206-207,共2页 Pediatric Emergency Medicine
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