摘要
目的探讨呼吸衰竭新生儿机械通气时呼吸力学特征及临床意义。方法对46例机械通气的呼吸衰竭患儿,进行呼吸力学指标监测及血气分析检查。结果两组患儿呼吸系统动态顺应性随疾病的好转逐渐增加[(0.36±0.20)ml/(cmH2O·kg)vs(55±0.1)ml/(cmH2O·kg),(0.33±0.2)ml/(cmH2O·kg)vs(0.43±0.1)ml/(cmH2O·kg)],两组患儿每分通气量在撤机前均有明显升高[(0.45±0.2)L/minvs(0.65±0.2)L/min,(0.43±0.4)L/minvs(0.60±0.3)L/min],呼吸系统动态顺应性和每分通气量与呼吸衰竭的严重程度及并发症的发生有关,呼吸系统动态顺应性与氧合指数呈显著负相关(r=-0.615),与每分通气量呈显著正相关(r=0.618)。结论呼吸衰竭新生儿机械通气时动态监测呼吸力学,可以判断肺部病变的严重程度和呼吸循环系统的并发症,评估通气策略,掌握撤机时机。
Objective To explore the characteristics of respiratory mechanics in neonatal respiratory failure with ventilation and its clinical significance.Methods We measured the indixes of respiratory mechanics and blood gas in 46 neonatal respiratory failure with ventilation.Results The indixes of respiratory mechanics in 46 neonatal respiratory failure with ventilation showed: The compliances of two groups were arised with recovering[(0.36±0.20)ml/(cmH_2O·kg) vs(55±0.1)ml/(cmH_2O·kg),(0.33±0.2)ml/(cmH_2O·kg) vs (0.43±0.1)ml/(cmH_2O·kg)] and correclated with severity and complication.The compliances negatively corrlalated with oxygenated index(r=-0.615) and correlated with MV(r=0.618).Conclusion Respiratory mechanics dynamic monitoring is beneficial in evaluating the severity of respiratory failure and complications,guiding mechanical ventilation management.
出处
《小儿急救医学》
2005年第3期201-203,共3页
Pediatric Emergency Medicine
关键词
呼吸衰竭
呼吸力学
新生儿
Respiratory failure
Respiratory mechanics
Neonate
