摘要
目的探讨不同液体张力对神经危重症患儿血清钠和神经症状的影响。方法根据入院血清钠检查值,将22例神经系统危重症患儿分为两组:低钠血症(Na+<135mmol/L)组应用1/2～1张液体,正常血钠组(135～145mmol/L)用1/5张液体。应用张力液体后1～3d均测血清钠、Glasgow评分,比较两组液体治疗后水电解质平衡情况。结果正常血钠组患儿,输1/5张液体3d后血清钠和Glasgow显著下降,评分:(11.4±2.1)与(10.4±1.8)分(P<0.05);血清钠:(136.2±4.8)mmol/L与(131.0±6.1)mmol/L(P<0.05),神经症状恶化。低血钠组患儿应用1/2～1张液体3d后血清钠和Glasgow评分显著升高:(7.9±0.9)与(9.1±2.2)(P<0.05);血清钠:(126.3±2.8)mmol/L与(141.2±7.0)mmol/L(P<0.001),神经症状得以改善。结论神经危重症患儿急性期应用≥1/2张液体,以防止出现低钠血症,加剧颅高压而恶化神经症状。
Objective To evaluate the effects of hypotonic intravenous fluid on Glasgow scale and serum sodium.Methods 22 patients were divided into two groups: low sodium group and normal sodium group.low sodium group(serum sodium<135 mmol/L)treated with fluid of 1/2 to isotonic; normal sodium group with hypotonic fluid of 1/5 tonicity.serum sodium level and score of Glassgow were assessed after of 1 to 3 days admission.Results the Glasgow scores and serum sodium of normal sodium group were dramatically decreased[scales:11.4±2.1 vs 10.4±1.8,P<0.05; Na:(136.2±4.8)mmol/L vs (131.0±6.1)mmol/L,P<0.05].The low sodium group were significantly increased[scales:7.9±0.9 vs 9.1±2.2,p<0.05; Na:(126.3±2.8)mmol/L vs (141.2±7.0)mmol/L,P<0.001],neurological symptom improved.Conclusion We suggest that tonicity of fluid(≥1/2) be given to critically neurologic children,to prevent hyponatremia,intracranial hypertension and worsened neurological symptom.
出处
《小儿急救医学》
2005年第3期195-197,共3页
Pediatric Emergency Medicine
关键词
低张液
血清钠
危重症
Tonicity of fluid
Serum sodium
Critical illness
