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口服枸橼酸铁铵溶液在MRCP中的初步临床应用 被引量:4

The Preliminary Clinical Application of Oral Ferric Ammonium Citrate Solution in MRCP
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摘要 目的:研究使用枸橼酸铁铵(FAC)溶液作为胃肠道阴性对比剂在改善磁共振胰胆管成像(MRCP)图像质量中的应用价值。方法:对40例受检者分别进行服用FAC前和服用后5、10、15min的MRCP检查,采用厚层SSFSE序列成像,且参数保持一致,观察胃肠道信号的消除情况、图像质量的改善情况及药物的可接受性。结果:口服FAC后胃和十二指肠的对比信噪比均有明显下降,其中胃和十二指肠均表现为服药前与服药后5、10、15min的对比信噪比,均为P<0.001,同时十二指肠服药后10min与服药后15min,P<0.001;服药后5min与服药后15min,P<0.01;MRCP的图像质量由服药前的2.9298±1.2499增至10.8865±0.8137,P<0.001。受检者均可接受该药物,极个别有轻微不适,症状自行消除,均无延迟不良反应。结论:口服FAC溶液能有效且安全的消除MRCP图像中胃肠道的高信号,明显改善图像质量,更清晰显示胰胆管结构及病变部位,有利于临床诊断。 Objective:To study the clinical efficiency of negative gastrointestinal contrast medium FAC on magnetic resonance cholangiopancreatography (MRCP).Methods:Thick slice single-shot FSE sequence imaging was performed in all forty patients before and after FAC administration for 5,10,15 minutes with the same parameters.Observation was based on the extent to which the gastrointestinal signals were eliminated,to which the image quality was improved,and to whether the patients could accept.Results:After using FAC,the signal-to-noise (SNR) of stomach and duodenum were all decreased sharply.The SNR of stomach and duodenum before and after FAC ingestion for 5,10,15 minutes were all manifested P<(0.001.)The SNR of duodenum 10 and 15 minutes after FAC ingestion showed P<0.001,that after FAC ingestion for 5 and 15 minutes showed P<0.01.The image quality was significantly improved to 10.8865±0.8137 from primary 2.9298±(1.2499) (P<0.001).Conclusion:Oral FAC solution can effectively and safely suppress gastrointestinal signals,improve (image) quality significantly in MRCP,and makes more clear demonstration of the biliary and pancreatic ducts.
出处 《放射学实践》 2005年第6期508-510,共3页 Radiologic Practice
关键词 磁共振成像 胰胆管造影术 枸橼酸铁铵 Magnetic resonance imaging Cholangiopancreatography Ferric ammonium citrate
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参考文献7

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二级参考文献12

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