摘要
目的:分析骨单发性骨髓瘤的影像学表现特点,提高对此病的认识。方法:对8例手术或活检病理证实为单发性骨髓瘤的影像学表现进行分析。结果:所有病灶均为单骨发病,发生于胸椎2例,股骨2例,肋骨2例,髂骨1例,锁骨1例,2例确诊2～3年后发生多发性骨髓瘤。2例发生胸椎者呈溶骨性破坏及压缩性骨折改变;发生于锁骨和肋骨等表现为膨胀性骨质破坏,其中发生于肋骨者骨质破坏周围见较大软组织肿块影;发生于股骨者骨质破坏较局限,边界较清楚,病变周围骨质硬化不明显,有不同程度骨膜反应,周围软组织肿块不明显。MR检查病灶边界清楚,T1WI稍低信号,脂肪抑制T2WI高信号,明显均匀强化。结论:骨单发性骨髓瘤常发生于男性,发病年龄比多发性骨髓瘤小,全身症状不明显,病变部位不同表现也各不相同,但病变边界均清楚。CT和MRI能更清楚地显示单发性骨髓瘤,MRI还可无创性评估骨髓浸润,发现X线平片和CT所不能显示的病变。
Objective:To evaluate imaging manifestation characteristic of solitary plasmacytoma of!bone and to increase understanding of this disease.Methods:8 patients (6 males,2 females) with solitary plasmacytoma of bone confirmed by biopsy or operation were included in our study.The mean age was 44.4 years. Results:All Lesions affected single bone.2 lesions involved the thoracic vertebra,2 lesions the femur,2 lesions the rib,the other 2 lesions involved iliac bone and clavicle respectively.2 cases developed multiple myeloma after 2～3 years.Two thoracic vertebra lesions showed lytic destruction and compressed fracture.The Lesions located in rib and clavicle showed expansive osteolytic lesion and with soft tissue mass.Lesions in femur showed localized and well-defined osteolytic change with different degree of periosteal reaction without soft tissue mass and bone sclerosis.Most well-defined lesions showed iso- or slightly hypointense signal on T_1-weighted MR image and hyperintense on fat-suppression T_2-weighted MR image with markedly homogeneous enhancement on post-contrast MR imaging.Conclusion:Solitary plasmacytoma of bone usually occurs in male.Compared with multiple myeloma,the former has younger patient age and absence of system symptom.Lesions localized in different site have different manifestation but all show well-defined border.Computed tomography and MRI can depict the extent of solitary plasmacytoma of bone more clearly,MRI may evaluate bone marrow infiltration noninvasively,detect lesions which cannot be detected by X-ray and CT.
出处
《放射学实践》
2005年第6期482-485,共4页
Radiologic Practice
