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4-1BB/4-1BBL共刺激信号通路在T淋巴细胞活化和自身免疫性疾病中的作用 被引量:3

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作者 陈雪 王兰兰
出处 《中华风湿病学杂志》 CAS CSCD 2005年第6期356-359,共4页 Chinese Journal of Rheumatology
基金 国家自然科学基金资助项目(30470683)
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参考文献20

  • 1Croft M. Costimulation of T cells by OX40, 4-1BB, and CD27.Cytokine Growth Factor Rev, 2003, 14: 265-273.
  • 2Lee HW, Nam KO, Park SJ, et al. 4-1BB enhances CD8^+ T cell expansion by regulating cell cycle progression through changes in expression of cyclins D and E and cyelin-dependent kinase inhibitor p27kipl. Eur J lmmunol, 2003, 33: 2133-2141.
  • 3Wilcox RA. Tamada K, Flies DB, et al. Ligation of CD137 receptor prevents and reverses established anergy of CD8^+ cytolytic T lymphocytes in vivo. Blood, 2004, 103: 177-184.
  • 4Bukczynski J, Wen T, Watts TH. Costimulation of human CD28 T cells by 4-1BB ligand. Eur J Immunol, 2003, 33: 446-454.
  • 5Kim J, Choi SP, La S, et al. Constitutive expression of 4-1BB on T cells enhances CD40^+ T cell responses. Exp Mol Med, 2003, 35:509-517.
  • 6Ebata T, Mogi S, Hata Y, et al. Rapid induction of CD95 ligand and CD4^+ T cell-mediated apoptosis by CD137 (4-1BB) costimulation. Eur J Immnnol, 2001, 31: 1410-1416.
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  • 8Bradley JR, Pober JS. Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene, 2001, 20: 6482-6491.
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同被引文献60

  • 1陈佳佳,李兰娟.B7-CD28家族共刺激途径的研究进展及其临床意义[J].国外医学(流行病学.传染病学分册),2004,31(6):334-338. 被引量:3
  • 2陈志平,刘贞富.可诱导共刺激分子与自身免疫性疾病[J].中华风湿病学杂志,2005,9(4):247-250. 被引量:1
  • 3Pankuweit S,Ruppert V,Maisch B.Inflammation in dilated cardiomyopathy[J].Herz,2004,29(8):788-793.
  • 4Maerten P,Kwon BS,Shen C,et al.Involvement of 4-1BB (CD137)-4-1BB ligand interaction in the modulation of CD4+T cell-mediated inflammatory colitis[J].Clin Exp Immunol,2006,143(2):228-236.
  • 5Vinay DS,Kwon BS.Immunotherapy targeting 4-1BB and its ligand[J].Int J Hematol,2006,83(1):23-28.
  • 6Aretz HT,Billingham ME,Edwards WD,et al.Myocarditis:A histopathologic definition and classification[J].Am J Cardiovasc Pathol,1987,1(1):3-14.
  • 7Kim YJ,Han MK,Broxmeyer HE.4-1BB regulates NKG-D costimulation in human cord blood CD8+ T cells[J].Blood,2008,111(3):1378-1386.
  • 8Habib-Agahil M,Phanl TT,Searle PF.Co-stimulation with 4-1BB ligand allows extended T-cell proliferation,synergizes with CD80/CD86 and can reactivate anergic T cells[J].Int Immunol,2007,19(12):1383-1394.
  • 9Vinay DS,Cha K,Kwon BS.Dual immunoregulatory pathways of 4-1BB signaling[J].J Mol Med,2006,84(9):726-736.
  • 10Cannons JL,Choi Y,Watts TH,et al.Role of TNF receptor associated factor 2 and p38 mitogen -activated protein kinase activaton during 4-1BB dependent immune response[J].J Immunol,2000,165(11):6193-6204.

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