摘要
血管加压素（ＡＶＰ）和促肾上腺皮质激素（ＡＣＴＨ）是体内调节水代谢平衡的重要激素。本文对１４例急性脑外伤病人血中ＡＶＰ、ＡＣＴＨ的含量进行了测定，结果发现：脑外伤后４８小时、６～１０天血中ＡＶＰ、ＡＣＴＨ含量明显升高。ＡＶＰ可增加脑损伤区毛细血管对水的通透性，加重脑水肿。推测ＡＶＰ／ＡＣＴＨ的比例失调可能是导致严重脑水肿的重要因素。
Arginine vasopressin(AVP)and adrenocortlcotrophic hormone(ACTH) are the important hormones which can regulate the balance of water metabolism in vivo.Thelevels of AVP and ACTH were determined in the blood of 14 patients with acute head injury.At 48 hours and 6～10days after head injury, the levels of AVP and ACTH in the blood increased obviously.AVP could reinforce the permeability of capillary to water in injury areas,and made encephaledema become severe.It is suggested that the disorder of the proportion between AVP and ACTH may be an important factor resulting in severe encephaledema.
出处
《中国冶金工业医学杂志》
1994年第3期134-135,共2页
Chinese Medical Journal of Metallurgical industry
关键词
脑损伤
血液
血管加压素
脑水肿
ACTH
Head injury
Blood adrenocorticotrophic hormone
Arginine vasopressin
Encephaledema
