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糖尿病肾病发病炎症机制研究进展 被引量:46

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摘要 越来越多的实验与临床研究表明炎症是糖尿病肾病(Diabeticnephropathy,DN)发生与持续进展的关键因素,本文概述了DN发病炎症实验与临床研究证据、可能的机制及干预措施,为进一步延缓或逆转DN的进展提供新的方向。
出处 《国外医学(泌尿系统分册)》 2005年第3期363-367,共5页 Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
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参考文献20

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  • 2Utimura R, Fujihara C, Clarice KF, et al. Mycophenolate mofetil prevents the development of glornerular injury in experimental diabetes. Kidney Int,2003,63:209-216.
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二级参考文献5

  • 1Sassy-Prigent C, Heudes D, Mandet C, et al. Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats. Diabetes, 2000, 49: 466-475.
  • 2Juna F N, Carmen M, Manuel M, et al.Inflammatory parameter are independently associated with urinary albumin in type 2diabetes mellitus. Am J Kidney Dis,2003, 42: 53-61.
  • 3Utimura R, Fujihara CK, Mattar AL, et al.Mycophenolate mofetil prevents the development of glomerular injury in experiment diabetes. Kidney Int, 2003,63: 209-216.
  • 4Romero F, Rodriguez-Iturbe B, Parra G,et al. Mycophenolate mofetil prevents the progressive renal failure induced by 5/6renal ablation in rats. Kidney Int, 1999,55: 945-955.
  • 5Kitada M, Koya D, Sugimoto T, et al.Translocation of glomerular p47phox and p67phox by protein kinase C-activation is required for oxidative stress in diabetic nephropathy. Diabetes, 2003, 52:2603-2614.

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