摘要
目的:观察卡维地洛对慢性心力衰竭患者心率的影响。方法:6 0例入选患者在原有治疗的基础上加用卡维地洛,初始剂量3.12 5毫克/天,两周加倍,逐渐加到目标剂量2 5毫克/天,持续到研究结束。结果:治疗后患者静息心率、运动最快心率明显下降(P <0 .0 0 1,P <0 .0 0 1)。结论:慢性心衰患者加用卡维地洛可以改善静息心率和运动时心率,从而提高运动耐受性。
Objective:To evaluate the effects of carvedilol on heart rate in patients with congestive heart failure.Methods:The sixty patients received routine treatment was added with carvedilol.The starting dose was 3.125mg/d,then double the doses every two weeks,the rarget dose was 12.5mg/d twice daily after 6 weeks and the dose kept without alterations during the study period.Results:The patients showed rdeuced resting heart rate,maximal heart rate on exercise(P<0.001,P<0.001).Conclusions:patients with heart failure received carvedelol therapy can improve their reasting heart rate and their heart rate control on exercise,thus the exercise toler0ance can be improved.
出处
《大同医学专科学校学报》
2005年第1期9-10,共2页
Journal of Datong Medical College
