摘要
目的:探讨心肌肥厚患者冠脉血流与左室舒张功能障碍关系。方法:采用彩色多普勒超声仪,进行经胸超声心动图(TTE)测量40例心肌肥厚患者和20例正常人冠状窦、二尖瓣及肺静脉血流频谱。结果:心肌肥厚患者冠状窦直径、前向血流和净前向血流流速积分(VTlnet)明显高于正常对照组;冠状窦前向血流和VTInet与左室舒张功能障碍的多项指标存在相关关系;肺静脉舒张末期逆行血流量最大流速之间均存在明显正相关(r=0.50、r=0.47、r=0.43、r=0.42、P均<0.05)。结论:冠循环血流动力学的改变可能是心肌肥厚患者舒张功能受损的机制之一。
objective: To study relationship between coronary circulation and left ventricular diastolic function in patients with cardiac muscle hypertrophy. Methods:Mitral,pulmonary venous and coronary sinus flow velocity variables were measured by transthoracic echocardiography in 40 cases with cardiac muscle hypertrophy and 20 cases with control subjects. Results: Patients with LVH had higher peak velocity of late transmittal blood flow(A wave), velocity time integral (VXI) of A wave and lower index of early versus late flow (E/A ratio) than those of control subjects. Patients with LVH had lower peak diastolic velocity of pulmonary vein than that of control subjects. The ratio of pulmonary venous diastolic and systolic flow velocities (S/D ratio), pulmonary venous A wave velocity and its duration were higher in patients with LVH compared with control subjects. The net forward flow velocity time integral (VTInet) , forward flow and diameter of coronary sinus were higher in patients with LVH compared with control subjects. There were significant positive Linear correlation between coronary sinus forward flow and E,E/A, VTI-E,VTI-E/A, and pulmonary venous A wave velocity. (r=r=0. 50,r=0. 47,r=0. 43,r=0. 42,P 均<0. 05). There were also significant positive linear correlation between coronary sinus VTInet and E,E/A, VTI -E, VTI-E/A, and pulmonary venous A wave velocity. (r=0. 38,0. 55,0. 43,0. 47,0. 37,P<0. 05). Conclusion:The change of coronary circulation may represent a mechanism for impaired diastolic function in patients with CMH.
出处
《中国民康医学》
2005年第5期226-228,共3页
Medical Journal of Chinese People’s Health
关键词
超声心动描记术
心脏肥大
心室功能
Eehocardiography
Heart hypertrophy
Ventricular function
