摘要
本文报道广西上林县用甲苯达唑药盐，分０．６％、０．３％、０．１５％三个浓度分别供Ⅰ、Ⅱ、Ⅲ组居民作生活盐食用，每人服药盐５００ｇ，约服用３０ｄ，每人服用甲苯达唑总量Ⅰ、Ⅱ和Ⅲ组分别为３ｇ、１．５ｇ和０．７５ｇ，每年进行一次，共三次，以防治钩虫病。结果三组居民钩虫感染率从服药盐前的７１．１％、５７．９％和６１．６％均降至０。停止服药后，经４～５年的远期效果考核，三个组的居民钩虫感染率和土壤钩蚴阳性率均为０。
To search for a convenient and effective method of preventing and curing hook-worm disease,a medicated-salt made of mebendazole mixed with salt in different concentrationwas supplied for residents as meal-salt.Three concentration grades of 0.6%,0.3%and 0.15%were used in group-Ⅰ,group-Ⅱand group一Ⅲ of the residents respectively.The medicated-salt administered was 500g per person within about 30 days. The result showed that egg negativeconversion rates in group-Ⅰand group-Ⅱwas 100.0%; in group-Ⅲwas 78.9%.This regime was conducted once a year for three years.The total amount of the drug administered ingroup Ⅰto ⅢWas 9,4.5 and 2.25g per person respectively.As the result,hookworm infectionrates dropped to 0%from 71.1%in group-Ⅰ,from 57.9%in group-Ⅱand from 61.6% in group-Ⅲ。4-5-year-follow-up observation showed that the hookworm infection rate in theresidents and the positive rate of hookworm larvae in soil all dropped to zero in three groups.
出处
《中国寄生虫病防治杂志》
CSCD
1994年第3期165-167,共3页
Chinese Journal of Parasitic Disease Control
关键词
果苯达唑
药盐
钩虫感染
Mebendazole medicated-salt ancylostomiasis
