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前列腺素E_1防治游离皮瓣术后血管危象的临床研究 被引量:10

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摘要 目的:研究前列腺素E1(PG E1)在显微外科游离皮瓣移植术后防治血管危象的作用。方法:以我科连续收治的72例游离皮瓣移例植术后患者为研究对象,34例为治疗组,38例为对照组,治疗组除常规治疗外,手术当天即给予前列腺素E1静脉点滴,疗程为5d,对照组予以常规治疗,从血管危象发生的有无、再植皮瓣血运情况、伤口愈合情况等几方面来综合判断治疗效果。结果:治疗组游离皮瓣移植术后血管危象的发生率为0,对照组血管栓塞所致的发生率为5.4%。两组对比差异有显著意义(P<0.05);治疗组的疗效总优良率达94.1%,对照组为89.2%,差异有统计学意义(P<0.05);而两组的凝血状态差异无显著意义(P>0.05)。结论:前列腺素E1用于游离皮瓣移植术后预防血管危象具有较好疗效,有临床应用价值。
出处 《实用医学杂志》 CAS 2005年第8期858-859,共2页 The Journal of Practical Medicine
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