摘要
目的:探讨晚期前列腺癌综合治疗方法。方法:对50例晚期前列腺癌采用经尿道前列腺汽化电切+双侧睾丸切除+雄激素受体阻断疗法。结果:IPSS评分由术前平均26.4分降至术后平均9分,生活质量评估由术前平均5.1分降至术后平均1.5分。最大尿流率由术前平均5.1m L/s升至术后平均15.2m L/s,残余尿量由术前平均142m L降至术后平均26m L。术后随访6个月～6年,5例癌性死亡,死亡率10%。结论:经尿道前列腺汽化电切对晚期前列腺癌并下尿路梗阻的治疗安全可靠,结合双侧睾丸切除及雄激素阻断治疗能起到协同治疗作用,可进一步提高疗效。
Objective To evaluate the process and efficiency of combined therapy in the treatment of advanced prostate carcinoma. Methods Fifty cases of advanced prostate carcinoma were treated by transurethral electro vaporization excision with orchiectomy and oral flutamide. IPSS, life quality evaluation, the maximum flow rate and residual urine were evaluated after operation. Results IPSS decreased from 26.4 preoperatively to 9 postoperatively and the life quality evaluation decreased from 5.1 preoperatively to 1.5 postoperatively. The maximum flow rate increased from 5.1 mL/s preoperatively to 15.2 mL/s postoperatively. Residual urine decreased from 142 preoperatively to 26 postoperatively. 6 months to 6 years after operation, 5 patients were died of prostate carcinoma, the death rate was 10%. Conclusions Advanced prostate carcinoma and urethral obstruction could be treated by transurethral electro vaporization excision safely and reliably, and combined therapy with orchiectomy and oral flutamide could improve the therapeutic efficiency.
出处
《实用医学杂志》
CAS
2005年第8期814-815,共2页
The Journal of Practical Medicine
