摘要
目的探讨早孕期经宫颈吸取绒毛术的安全性及临床价值。方法对36例有产前诊断指征的孕妇采用超声引导下经宫颈吸取绒毛术,取得绒毛标本送实验室进行相关检测。结果1次取材成功为27例,2次取材成功为7例,总成功率94.4%。主要不良反应有腹痛,阴道少量流血。无1例早期发生流产。选择继续妊娠的22例孕妇中有21例足月产出正常活婴,1例于妊娠25周因胎膜早破而流产。结论早期产前诊断手段,能避免孕中期的引产手术,减少缺陷儿的出生,有助于优生优育。
<Abstracts>Objective To evaluate the safety and clinical value of chorionic villus sampling via the cervix for prenatal diagnosis of early pregnancy. Method Thirty-six women with early pregnancy who required prenatal diagnosis received chorionic villus sampling via the cervix under the guidance by ultrasonography for laboratory examination of the samples. Results Villus sampling was performed successfully in 27 of the 36 cases in a single operation, whereas a second operation for sampling was needed in another 7 cases, with a total operation success rate of 94.4%. The side effects included abdominal pain and vaginal bleeding in small quantity. In the 22 women who chose to continue the pregnancy, one woman experienced miscar- riage at the 25th gestational week due to premature rupture of the membrane, and all other women gave birth to normal full-term infants. Conclusion Chorionic villus sampling via the cervix under the guidance by ultrasonography is effective and safe for prenatal diagnosis in early pregnancy to help avoid induced abortion in mid-pregnancy and the occurrence of fetal defects.
出处
《第一军医大学学报》
CSCD
北大核心
2005年第4期427-428,共2页
Journal of First Military Medical University
关键词
早孕期
绒毛吸取术
产前诊断
early pregnancy
chorinic villi sampling
prenatal diagnosis
