摘要
目的 研究急性肠系膜缺血后各时段酶谱变化规律,为临床早期诊治该病提供帮助。方法 将36只家兔分为动脉阻断、静脉阻断、动静脉阻断3组,每组12只。每组动物分别于阻断前、阻断后1、3、6、9h抽静脉血,检验血清内丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、碱性磷酸酶(ALP)、谷酰转酞酶(γ-GT)、肌酸激酶(CK)、肌酸激酶同工酶(CK MB)、乳酸脱氢酶(LDH)水平。同时观察肠管的颜色变化。结果 各组家兔肠管在血管被阻断3h后开始发生坏死,同时ALT、AST、ALP、γ- GT、LDH均有明显升高。结论 血清酶谱检查有助急性肠系膜缺血性疾病的诊断。
Objective To study the change regulation of enzymes in serum for the diagnosis and treatment of acute mesenteric ischemia by earlier period. Methods Thirty-six of rabbits were divided into three groups included from artery, vein and artery with vein by interrupted in mesenteric vessels respectively and there was twelve rabbits in every groups. It was observed that ALT, AST, ALP, γ-GT, CK, CK- MB, LDH in serum at mesenteric vessels pre-interrupted and post-interrupted 1,3,6,9 h respectively and the bowel color variety was observed at the same time too. Results After 3 h from post-occluded of mesenteric vessels, among the three groups there was bowel infarction and ALT, AST, ALP, γ-GT, LDH in serum all to obviously go up. Conclusion It is beneficial to diagnosis of acute mesenteric ischemia at earlier by the examination of enzymes in serum.
出处
《中华外科杂志》
CAS
CSCD
北大核心
2005年第7期430-432,共3页
Chinese Journal of Surgery
