摘要
研究目的探讨胸腹水α_1-抗胰蛋白酶在单纯肝硬化腹水与恶性肿瘤胸腹水中的鉴别价值.方法采集恶性肿瘤患者的胸水或腹水及单纯肝硬化患者的腹水，用速率散射比浊法检测α_1-抗胰蛋白酶水平，测定结果进行t检验.结果37例恶性肿瘤胸腹水α_1-抗胰蛋白酶测定值为0.90～4.60/dl，30例单纯肝硬化腹水α_1-抗胰蛋白酶测定值为0.45～2.20mg/d，（P＜0．001）。α_1-抗胰蛋白酶含量1.01mp／dl作为鉴别单纯肝硬化腹水与恶性肿瘤胸腹水的界值，其敏感性为93.94％，特异性为92.5％,阳性预示值为93.94％，阴性预示值为92.59％。结论恶性肿瘤胸腹水α_1-抗胰蛋白酶含量明显高于单纯肝硬化腹水，并可作为诊断恶性肿瘤胸腹水的一个指标.
objeotive Probing into the diagnostic value of alphα_1-antitrypsin (α_1-AT) in pleural fluid and ascites for malignant tumor and cirrhosis.Method Thirty seven patients with malignant tumor and 30 patients with cirrhosis of liver were observed comparatively. The α_1-AT in pleural fluid and ascites was deterrnined by rate nephelometry The ttest was used in statistical anafysis.Results α_1-AT levels in pleural fluid and ascites were significantty elevated in patiemts with malignant tumor as compared with those cirrhosis (P＜0.001)Conclusin α_1-AT level in pleural fluid and ascites can be taken for an important index to differentiate malignant tumor and cirrhosis of liver.
出处
《新乡医学院学报》
CAS
1994年第2期166-167,共2页
Journal of Xinxiang Medical University
关键词
胸水
腹水
肿瘤
α1
抗胰蛋白酶
pleural fluid
ascites
malignant tumor, alpha1-Antitrypsin
rate nephelmetry
