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慢性阻塞性肺疾病及肺心病患者红细胞变形性变化及其相关因素分析

The Erythrocyte Deformability in Patients with Chronic Obstructive Lung Disease or Pulmonary Heart Disease and the Analysis of Relative Factors
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摘要 观察慢性阻塞性肺病、肺心病患者红细胞变形能力的变化趋势及红细胞变形性与红细胞压积(Hct)、pH、PaO_2及PaCO_2的关系。发现:1.慢性阻塞性肺病与肺心病患者红细胞变形能力大部明显下降。2.肺心病患者红细胞变形能力变化与心功能状态有关。3.在慢性阻塞性肺疾病(COPD)病程进展的一定阶段,pH、PaCO_2与红细胞变形性无直线相关关系,Hct、PaO_2与红细胞变形性分别呈直线正、负相关关系,可能是机体的一种代偿反应。 This study was undertaken to examine the alteration of erythrocyte deformabili-ty in patients with chronic obstructive lung disease or pulmonary heart disease and the relation between the deformability and Hct, pH, Pa02, PaCO2. It was suggested that (1) the def ormability index (DI) of red cells in patients was lower than that in control groups (2) The alteration of erythrocyte def ormability in patients with chronic pulmonary heart disease was correlative with the cardiac function) (3)There was no relationship between DI and the Hct, PaO2 in class III of pulmonary heart disease, but there was a significant inverse correlation between erythrocyte deform-ability and PaO2 and direct correlation between DI and Hct. It might be a compensatory reaction of body.
作者 曹洁 郭仓
出处 《天津医药》 CAS 1994年第2期83-85,共3页 Tianjin Medical Journal
关键词 阻塞性 肺疾病 红细胞变形性 COPD erythrocyte deformability shear stress
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