摘要
采用羟基磷灰石粉末。有机多聚体、粘结剂和植物干燥叉枝研制成多孔型准基磷灰石陶瓷人工骨，有独特的连通孔道。通过热源试验、溶血试验、急性全身毒性试验和细胞毒性试验评价其生物相容性。实验结果表明，多孔型羟基磷灰石陶资人工骨不致热，不致溶血，无毒性，对培养的小鼠成纤维细胞的生长、增殖、代谢无不良影响，培养细胞形态正常．因此，可以认为这种人工骨具有优良的生物相容性。
3rdroxyapetite (HA) power, orchid POI￣, dried vegetable stems ac gelatin were used toproduce POProus hwtoxyapetite cd￣ic artifidal bone, which contained peicular interconnectedcanaliculi. Its biocompehbility was evaluated by Pyrogen test,hemolguis tact and toxicity teds. TheresultS sh(twed that the porous HA ceramiC does not lead to hemolwis,P￣niC reachon and acuteSystemic toxicity. Obervation of the affect on culture cells was Cartted out by uSing L-- 929 cells.The results showed that the POrous HA Cersmic has no ichlence on growth, reproduction andmetabolism,and no change in mlorphology of L-- 929 cells. The above r￣lts avow that the potous HAceramic has a good hi￣mpetibility.
出处
《苏州医学院学报》
1994年第2期87-89,101,共4页
Acta Academiae Medicinae Suzhou
基金
国家自然科学基金
关键词
羟基磷灰石
陶瓷
细胞培养
人工骨
hydroxyapeite Iceramic lbiocompetibility Iced cultUre
