摘要
对４５例Ⅱ期乳腺癌标本的核仁组成区嗜银蛋白（ＡｇＮＯＲ）、ＤＮＡ含量、Ｓ期细胞百分比（ＳＰＦ）进行光镜和流式细胞分析仪测定。结果，乳癌异倍体、ＳＰＦ、ＡｇＳＮＯＲ均明显高于二倍体的乳癌。腋淋巴结有转移组较阴性组的ＡｇＮＯＲ、ＳＰＦ、异倍体百分率明显增高。随访结果提示，患者无癌生存期与ＡｇＮＯＲ、ＳＰＦ有关。
sing a flow cytometry to analyze parffin─ embedded patological material of 32 tumors andfresh material of 13 tumors,cellular DNA─ ploid and S─ Phase fraction(SPF) were measured in 45potients with Primary infiltrating ductal breast cancer(phase I ). Silver--binding nucleolar organizerregions(AgNORs) were counted in section of runtinely processed parffin--embeddes blocks(cutoff: 5cells). The level of SFT and AgNORs of the aneuploid tumors were highet than that in ploid tumors.The tumors with axillary nodes involement had higher AgNOTs,SPF and aneuploid. By means ofmultivariate analysis using a stepwise Cox model it was found that AgNORs,SPF were importantprognostic factors to DFS in PatientS with Primary breast cancer.
出处
《苏州医学院学报》
1994年第1期4-7,共4页
Acta Academiae Medicinae Suzhou
