摘要
分析７６例血栓闭塞性脉管炎患者和５５例正常对照者的红细胞免疫功能及调节、体液免疫和细胞免疫。结果表明：①活动期病人红细胞ｃ３ｂ受体活性降低，红细胞免疫复合物花环率增高，红细胞免疫促进因子降低而抑制因子升高。②ＩｇＧ，ＩｇＭ和ＣＩＣ含量升高，补体溶解免疫复合物活性则明显下降。③ＣＤ_３、ＣＤ_４和ＣＤ_８细胞百分率均明显低于正常对照组；中性粒细胞吞噬功能增强，其发光值超过正常人的３．５倍。由此提示，血栓闭塞性脉管炎是一种自身免疫紊乱性疾病。
In this paper we analysed some changes of RBC immunological function, regulator fators, humoral and cellular immunity in 76 cases of patients with thrombangiitis obliterans (TAO). 55 cases of blood donors served as normal controls.The results showed that : (1) activity of RBC C3b receptor of patients in active stage reduced, the rate of RBC immune complex rosette raised. The value of RBC immune adherence enhance(RFER) lowered and RBC immune adherence inhibitory factors (RFIR)raised. (2)The value of IGG, IGM and circulation immune complex(CIC) increased and activity of complement mediated solubilization of immune complex cut down markedly.(3) percentage of CD3、CD4 and CD8 was much lower than that of normal controls.Phagocytic function of neutrophile was enhanced and its value of chemiluminescent response of whole blood was 3. 5 times more than that of normal controls. Hence, it was concluded that TAO was one of autoimmune disorders.
出处
《泰山医学院学报》
1994年第1期16-21,共6页
Journal of Taishan Medical College
关键词
体液免疫
血栓
闭塞性
脉管炎
red cell immune function
humoral immunity
thromboangiitisobliterans
