摘要
在15年间920例次异体尸肾移植的患者中,发现14例总结核感染并发症,发生率为1.6%,其中肺结核感染11例,肾结核感染6例。12例的结核诊断依据由临床表现,胸片PCR结核杆菌DNA序列检测及肾活检等综合力式确定,2例于死后尸解才确立诊断。经抗痨治疗后10例治愈,2例死亡。文章对肾移植后结核感染并发症的临床症状、诊断和治疗等进行了讨论。
uring a
15-year period ,14 cases of mycobacterial infection (tuberculosis)developedin 920 rerial
transplant recipients at Chang Zheng hospital,an incidence of 1.6 percent.Acombinative
deabnosis was established in 12 patients,which includ clinical manifestations,chest
roentgenugram. PCR amplification of a repetitive DNA specific to mycobacterialtuberculosis
and allograft biopey, etc. The diagnosis of other two petients was made atautopsy,The moat
common symptom was fever.After anti-tuberculosis therapy,tenpetients were cured and four
failed.beuse of atypical presentations and rapid disseminationof mycobacterial infections in
immunosuppressed patients,early diagnosis and treatment is ofutmost importance. The
diagnosis and treatment of mycobacterial infections in renaltransplant recipients are
discussed.
出处
《肾脏病与透析肾移植杂志》
CAS
CSCD
1994年第3期185-188,共4页
Chinese Journal of Nephrology,Dialysis & Transplantation
关键词
结核感染
并发症
肾移植
病例报告
renal transplantation
mycobacterial infecton
complication