摘要
应用蝮蛇抗栓酶３号（以下简称Ｓｖａｔｅ—３）治疗心血管病高凝状态２４例，剂量１．０ｕ稀释后静滴，ｑｄ，３周为一疗程。治疗后患者全血粘度、血浆粘度、血小板聚集率、组织纤溶酶原激活物抑制剂（ＴＰＩ）、血栓素Ｂ２（ＴＸＢ２）、组织纤维连结蛋白（ＦＮ）均有显著下降，而组织纤溶酶原激活剂（ＴＰＡ）、６－酮前列腺素Ｆα（６－Ｋｅｔｏ－ＰＧＦα）明显升高。提示，该药治疗心血管病高凝状态有效。
A preparation of Fushe Kangshuanmei (svate-3), 1.OU, for intravenous drip after dilution once daily. 21d as a course of treatment, was given to 24 patients with high coargulisis of various card iovascular disease. The blood and plasma viscosity, the rate of platelet aggregation, the plasminogen activator inhibitor (PAI) .the thromboxane B2(TXB2)and the fibronectin(FN)were all decreased and the tissue-type plasminogen activator(TPA)and the 6-Ketone-prostaglandina (6-ket-PGFα)were increased significantly following the medication.It is suggested that this remedy is useful for high coagulisis of cardiovascular diseaes.
出处
《蛇志》
1994年第3期11-14,共4页
Journal of Snake
关键词
蝮蛇抗栓酶
高凝状态
药理
疗效
snake venoms Fushe Kangshuanmei high coagulisis
