摘要
通过约束条件（Ｍａｒｋｏｖ熵，Ｇ＋Ｃ含量等选择约束因素）下的熵极大化导出核苷酸序列的碱基概率分布．理论值和实验资料的差别小于１０％．发现拉格朗日乘子随着物种进化有系统变化．
The probability distributions of bases in nucleotide sequences are deduced from maximum information principle (MIP) by maximizing the entropy (due to random mutatian of bases)under some constraints(Markovian entropy,G+C content,etc,due to selection).Twoformulations are given with respect to different selective constraints, The deviations of theo-retical distributions with experimental data are lower than 10%for most sequences. It is shown that the Lagrange multipliers change from species to species systematically which means the correlation of selective constrains with evolution.
出处
《内蒙古大学学报（自然科学版）》
CAS
CSCD
1994年第2期168-173,共6页
Journal of Inner Mongolia University：Natural Science Edition
基金
国家自然科学基金
关键词
最大信息原理
核酸序列
进化
maximum information principle nucleotide sequence evolution
