摘要
本文报告２１例自１９７５年以来经我院外科手术及病理检查证实的胃恶性淋巴瘤，其中１５例具备胃活检资料。复习全部临床、病理资料，进行免疫组化染色及临床随访，以探讨疾病的诊断及预后问题。结果显示：患者年龄偏轻、男女比例接近、病程偏长而全身状况较好与胃癌不同。内镜表现主要为息肉样、溃疡性及浸润性损害，以病变的多灶性、多形性及弥漫性为特征。组织学上高恶性多、Ｂ细胞性多，低恶性者多属ＭＡＬＴ来源。１４例随访者平均存活５．２年，７例胃镜复查无复发。由此表明，本病预后较好，内镜改变具特征性，免疫组化对区分低分化癌、真假恶淋及细胞来源颇有裨益，宜在活检中常规使用。正确认识反应性淋巴样增生与恶淋之间的演变过程对确定诊断、随访观察及预后判断十分重要。
Twenty-one cases of primary malignant lymphoma of the stomach with 15 biopsies from gastroscopy since 1975 from the department of pathology were studied.The chinical and pathological data were reviewed and a follow-up study,immunohistochemical staining were performed for diagnostic and prognostic approach to the disease.The results showed that the patients were rather young and little differenec in sex ratio.The clinical course was rather long with better pragnosis than that of gastric carcinoma.Endoscopically,polypoid,ulcerative and infiltrative lesions could be found because of polymorphic,multifocal and diffusive changes in characteristics. Histologically,more high-grade and B-cell malignancy and MALT origins could be seen. Fourteen cases followed-up have survived for 5.2 years in everage and 7 of them checked by endoscopy without recurrence.The results indicated a promising prognosis of the disease with typical changes in gastroscopic manifestation.Immunohistological staining is quite useful in differentiation of carcinoma pseudolymphoma from lymphoma and determination of origin of the tumour cells.It is crucial to distinquish the sequence of reactive lymphoid hyperplasia to malignant lymphoma.
出处
《内镜》
1994年第2期73-75,共3页
关键词
淋巴瘤
诊断
胃肿瘤
病理
Primary malignant lymphoma of the stomach
diagnosis
differenciation
