摘要
本文观察了铜仿膜透析器首次使用综合征的临床表现及其对透析患者IL-1(白细胞介素1)、TNPα(肿瘤坏死因子α)和C3(补体3)的影响。结果发现:透析后1h患者IL-1、TNFα和C3水平明显升高(P<0.01),与透析后1h首次使用综合征症状发生率较高相一致。膜的生物相容性是首次使用综合征的重要原因,新透析器高通透性是首次使用中症状性低血压的原因。
Cytokines have been
implicated in several dialysis related complication,To study the effect of firstuse of ciipropliane
membranes on cytokines preduction. 41 potients with chronic hemedialysis were investigated
duringfirst use cupropbane membrans. The levels of serum IL- 1 -TNFα and C3 in 13 cases
were measured at pre-diaiysis. 1 hr ,2 hr and 4 hr into treatment. The rcsults showed that the
concentration of serum IL-1 .TNFα and C3 were significantlyhigher in 1 hr of dislysis than that
of pre-dialysis. Mort of the symptoms of new dialyser syndrome occured in post-dialy-sis of 1
hr. The brrmpatibility and pormeability was the main cause of new diaiyser syndrome.
出处
《免疫学杂志》
CAS
CSCD
北大核心
1994年第2期124-126,共3页
Immunological Journal