摘要
对３１例重型乙型肝炎患者用放射免疫分析法检测血清中β＿２－Ｍ含量，并用免疫组化ＡＢＣ法检测肝内β＿２－Ｍ、ＨＢＡｇ和Ｔ细胞亚群的表达与分布。结果发现重型肝炎血清中β＿２－Ｍ含量显著增高，且与病情轻重相关；肝内浸润细胞中ＣＤ８￣＋细胞占优势，提示肝内β＿２－Ｍ、ＨＢｓＡｇ表达及ＣＤ８￣＋细胞的浸润与细胞损伤有关。
The levels of β_2-microglobulin(β_2-M)in serum and expression of β_2-M in liver tissue trom thirtyone pa-tients with severe hepatitis B were detected. The results showed that (1)the levels of β_2-M in patients were remarkably in-creased;(2)expression of β_2-M in pafients were closely correlated with liver damage of patients with severe hepatitis B.
出处
《免疫学杂志》
CAS
CSCD
北大核心
1994年第1期33-36,共4页
Immunological Journal
关键词
乙型肝炎
微球蛋白
抗原
CD8
T细胞
Severe viral hepatitis B.β_2-Microglobulin (β_2-M).Hepatitis B virus associated anttien (HBAg).CD8￣+cell
