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膀胱移行细胞癌外周血T淋巴细胞亚群的观察

Observation of Peripheral Blood T-cell Subpopulation in Bladder Cancer Patients
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摘要 对22例膀胱移行细胞癌(TCC)患者和18例对照行外周血T淋巴细胞亚群观察。 TCC患者外周血CD3和CD4明显降低(P<0.01),CD8无明显改变(P>0.05),CD4:CD8呈显著性 差异(P<0.05)。提示:TCC患者外周血T淋巴细胞免疫功能低下。 The T lymphocyte subpopulation of peripheral blood in 22 bladder cancer patients and 18 normal controls was neasured. The CD3 (total T-cells) and CD4 (helper T-cells) decreased significantly as compared with control group(P<0. 01). The CD8 (suppressor T-cell)had no significant difference (P>. 05). The CD4 : CD8 ratio had been lowered (P<0. 05). The results suggested that the reduced cellular immune function exist in patients with blaader cancer.
出处 《兰州医学院学报》 1994年第3期174-175,共2页 Journal of Lanzhou Medical College
关键词 膀胱移行细胞瘤 T淋巴细胞亚群 膀胱肿瘤 Biadder cancer T lymphocyte subpopulation
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参考文献4

  • 1张志义.恶性肿瘤临床基础研究[M]上海科学技术文献出版社,1985.
  • 2A. Greenstein,M. Pecht,I. Kaver,N. Trainin,Z. Braf. Characterization of peripheral blood T-cell subpopulation of bladder cancer patients[J] 1991,Urological Research(4):219~222
  • 3M. Shaw,P. Ray,M. Rubenstein,P. Guinan. Lymphocyte subsets in urologic cancer patients[J] 1987,Urological Research(3):181~185
  • 4Willem Otter. Immune surveillance and natural resistance: an evaluation[J] 1986,Cancer Immunology Immunotherapy(2):85~92

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