摘要
本文测定了45例感染儿和20例健康儿血清纤维结合蛋白(Fn)、转铁蛋白(Tf)、免疫球蛋白(Ig)含量。结果:①感染儿Fn(0.038±0.035g/L)明显低于健康儿(0.188±0.037g/L)(P<0.001),②45例感染儿中25例肺炎与20例非呼吸道疾病儿Fn均低于健康组(分别为0.033±0.029g/L和0.044±0.03g/L),P均<0.001)。25例肺炎儿中12例重型Fn(0.0190±0.0156g/L)较普通型(0.038±0.031g/L)降低(P<0.05)③感染儿Tf(1.247±0.854g/L)明显低于健康儿(1.999±0.251g/L)(P<0.001),感染儿IgG(9.593±3.041g/L)也明显低于健康儿(13.010±0.474g/L)(P<0.001);IgA、IgM无显著差异。表明:①Fn含量可作为揭示感染及判定感染严重程度的客观指标。②Tf值具有提示感染及评估铁营养状况的双重价值。
The content of Serum fibronetin(Fn),transferrin(Tf)and immunoglobin(Ig)in 45 cases of infected children and 20 cases of normal ones were measured.The results indicated that:(1)The Fn content in infected children was significantly lower than that in normal ones.(2)As for the 25 cases of pulmonitis patients,the Fn value in 12 cases of sevece ones was obviously lower than that in 13 cases of general ones.(3)The Tf value of the infected group was much lower than that of the normal group.(4)The result of IgG content was the same as that of Fn and Tf contents,respectively in infected and normal ones.But the difference in IgA and IgM values between infected and normal group has not been observed.The above results suggest as follows:(1)Fn value may be used alone as an objective index to determine whether or not a child is infected and the severity of infections disease.(2)Tf can be used as an index both to determine the exsitence of an infection and to estimate the ferrin nutritional status of a child.(3)Our expersiment has provided a guidance to judge the condition of diseased children and to cure patients in clinical practice.
作者
谷小华
崔雯
方丽辉
李荷华
李瑞炎
Gu Xiaohua;Cui Wen;Fang Lihui(Department of Pediatrics,Second Affiliated Hospital,Hubei Medical University,Wuhan 430071,China)
关键词
儿童
炎症
血液
纤维连接素
child
inflammation
carrier proteins/BL
transferrin/BL.
