摘要
本实验研究了不同浓度胰岛素对体外单个核细胞IL_2、IL_6诱生的影响。实验提示:胰岛素浓度为0.02μu/ml、20μu/ml时不影响单个核细胞IL_2,IL6_的产生。胰岛素浓度为2000μu/ml时能显著增加单个核细胞IL_2、IL_6的产生。结果表明:高浓度胰岛素才能增加外周血单个核细胞产生IL_2、IL_6的能力。
The effect of insulin on induction of IL_2 and IL_6 had been investigated when concentrations of insulin are 0.2μU/ml and 20μU/ml,the productions of IL_2 and IL_6 were not affected in peripheral blood monocytes,Howere,hish insulin level(2000μU/ml)significantly increased the IL_2 and IL_6 production in vitro.These results have demonstrated that only high insulin level induces productions of IL_2 and IL_6 in peripheral blood monocetys.
关键词
胰岛素
单个核细胞
白细胞介素
insulin
interleukin-2
interleukin-6
peripheral blood monocyte