摘要
测定了５０例婴幼儿极期、恢复期、正常儿童超氧化物歧化酶（ＳＯＤ）及血清脂质过氧化物（ＬＰＯ）含量，结果显示：肺炎极期ＳＯＤ活性明显低于正常对照组（Ｐ＜０．０１），血清ＬＰＯ含量明显高于正常对照组（Ｐ＜０．０１），表明自由基参与了肺炎的病理生理过程。联合应用大剂量抗氧化剂维生素Ｅ和维生素Ｃ佐治婴幼儿肺炎１０例，结果表明其临床治愈时间、ＳＯＤ活性及ＬＰＯ含量能较快恢复正常，提示在常规治疗基础上加用抗氧化剂治疗婴幼儿肺炎有助于肺炎的早日恢复。
Superoxide dismutase(SOD) and lipid peroxidation(LPO) contents in 50 infants with pneumonia in climax and convalescent stages were investigated.The result showed that, in the climax stage, the contents of the SOD were lower and LPO higher than thase in nomal chil-dren,and that free radical took part in the pathologic process of pneumonia. Using high dose of antioxidants(vitamin C and vitamin E),we treated 10 cases of pneumonia. The recovery time of pneumonia was shorter, SOD activity and LPO contents were quicker to recover to normal than those in the usual therapy group. Antioxidant therapy may be beneficial to pneumonia recovery.
出处
《河南医科大学学报》
1994年第3期225-228,共4页
Journal of Henan Medical University
关键词
肺炎
超氧物歧化酶
维生素
婴幼儿
pneumonia
superoxide dismutase
lipid peroxidation
vitamin C
vitamin E
infant
