摘要
本研究入选268例不稳定型心绞痛(UAP)和62例无Q性心肌梗塞患者(NQMI),随机分组作抗血栓治疗,单纯使用阿斯匹林或阿斯匹林加抗凝治疗(先用肝素,随后用华法令)共12周随访观察.结果发现,尽管在最大程度的药物治疗下,两组患者总缺血性事件发生率相似(27%),且NQMI组再梗塞和死亡发生率(17%)明显高于UAP组(7%).
268patients with unstable angina (UAP) and 62 with non-Q wave myocardial infarction (NQ-MI) were randomized to antithrombotic therapy with either aspirin alone, or aspirin plus heparin followed by aspirin plus war farm, and followed up for 12 weeks. It was found that patients with UAP or NQMI had a similartotal number of ischemic events (27%). However, those with NQMI had a significantly higher rate (17%) of re-infarction and/or death, compared with UAP patients (7%), in spite of maximal medical treatment.
基金
美国纽约心脏基金会等提供资助
