摘要
本文测定３２例青少年单纯性肥胖症的肾上腺皮质功能，结果显示：①２１例病人血浆总皮质醇（ｐｌａｓｍａｔｏｔａｌｃｏｒｔｉｓｏｌ，ＰＴＣ）昼夜节律存在不同程度、不同类型的异常；②尿游离皮质醇（ｕｒｉｎａｒｙｆｒｅｅｃｏｒｔｉｓｏｌ，ＵＦＣ）的含量在正常范围；③地塞米松抑制筛查试验正常。说明约６５．６％青少年单纯性肥胖症的肾上腺皮质功能活动水平较高，但对地塞米松的反馈抑制作用仍十分敏感，这与正常青少年及柯兴综合征患者均不同。
The circadian rhythm of plasma total cortisol(PTC)levels and urinary free cortisol(UFC)were determined, and dexamethasone supressive screening test was performed in 32 cases of adolescent with simple obesity.The results showed that:(1) The circadian rhythm of PTC was abnormal in extent and type in 21 cases,(2) The UFC and dexamethasone suppressive screening test were normal in all cases.These indicated that the adrenocortical function in 65.6% of the adolescent with simple obesity was hyperactive,but highly sensitive to the nerative freedback suppressive effect of of dexamethasone.The differenence in adrenocortical function in cases of simple obesity from that in normal adolescent and adolescent with Cushing's syndrome was discussed.
出处
《哈尔滨医科大学学报》
CAS
1994年第5期417-419,共3页
Journal of Harbin Medical University
关键词
肾上腺皮质功能
青少年
肥胖病
Adrenocortical Function
Adolescent
Simple obesity
