摘要
对从贵州省安顺地区伤寒暴发流行患者分离并经药敏试验获得的111株多重耐药性伤寒沙门氏菌,做了接合性R质粒的检测。接合性R质粒检出率在氨苄青霉素(AP)、羟氨苄青霉素(AO)、氧哌嗪青霉素(PR)、四环素(TC)、卡那霉素(KM)和缝霉素(SM)6种抗生素耐药标记菌株中最高,均达98％以上,氯霉素(CM)耐药标记菌株的检出率为75.7％。并且证实流行菌株R质粒的基本耐药性传递类型为。AP、AO、PR、TC、KM,CM、SM和AP、AO、PR、TC、KM、SM两种模式。
Conjugative R plasmids were detected in 111 strains cf Salmonella typhi from patients and drug-sensitivity was detected in an epidemic outbreak of typhoid fever occurred in Anshun area of Guizhou Province.The percentage of conjugative R plasmids from strains marked by six antibiotic resistance-ampicillin (AP) , amoxycillin (AO) , piperacillin (PR), tetracycline(TC), kanamycia(KM)and streptomycin(SM)-was the highest(over 98%).The strains marked by chloromycetin(CM)drug resistant accounted for 75.7% .The two patterns of the basic R plasmid AP, AO, PR, TC, KM, CM, SM and AP AO, PR, TC, KM, SM were proved.
出处
《白求恩医科大学学报》
CSCD
1989年第3期289-242,共1页
Journal of Norman Bethune University of Medical Science
关键词
伤寒
沙门氏菌
耐药
R质粒
Salmonella typhi Drug resistance, microbial Multiple drug resistance R plasmids Conjugative test
