摘要
当恒定电场或交变电场垂直作用于完整肌纤维时,发现其退偏率随电场强度的增加呈先下降后上升的趋势。这是由于电场能使肌纤维一侧的膜去极化,导致肌质网内钙离子的释放,促使肌动蛋白增加新的活化位置,使一部分弱结合横桥向强结合过渡,另一部分自由横桥向结合横桥过渡,造成退偏率随电场强度的增大呈先下降的趋势。随着电场强度的进一步增加,钙离子的释放趋向饱和,而肌丝的电极化增强造成粗肌丝对横桥的静电吸引力增强,使退偏率逐渐回升。磁场作用证实了这一作用机理的合理性。
When a constant or altenative electric field is perpendicularly acted on the frog intact muscle fibres, it is displayed that the depola-rization ratio of the diffraction light goes down at first, then goes up with increase of the electric field strength, We consider that the elec-tric field should induce one side of the membrane potential to depoalrize, and it can take the SR release the Ca ions. Due these Ca ions the new active sites at the actns would be happened, so some of the weak coupling cross-bridges are transfered to the strong coupling' s, and some of the free Cross-bridfes are change d to the coupling' s. It is why the depolari-zation ratio of the diffraction light is decreased at first. When the electric field strength is increased to a certain value. the Ca ions con-centration within the fibre towards to a satuated value. and the SR couldn' t release more Ca ions. But with increasing the electric field the electrically polarization of the myosons is increasing the electric field elec- trostatic attractive force between the thick filament and then the cross-bridge is more stronbt and strong, the resault is that the depolarization ratio goes up.experimental data of the magnetic field stimulation and the electromicroscopic graphs support this contraction modeling.
出处
《光电子.激光》
EI
CAS
CSCD
北大核心
1994年第2期76-81,共6页
Journal of Optoelectronics·Laser
基金
国家自然科学基金