摘要
用化学方法成功地将放射增敏剂灭滴灵连接到对癌细胞具有定位作用的原卟啉上，通过红外光谱、紫外可见吸收光谱、质谱、核磁共振谱和元素分析等手段确证了其结构。经动物实验证明，放射增敏效果较好。
The metronidazole as a radio-sensitizer was chemically combined with protoporphyrin which has shown some orientating effects on cancer cells.The structure of this new compound was confirmed by the UV,IR spectra and elementary analysis.It is found that the porphyrin has shown some potential drug effect in aminal test and the decrease of dosage and reduction of toxicity.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1994年第1期5-8,共4页
Chemical Journal of Chinese Universities
基金
南京大学配位化学研究所国家重点实验室资助
