摘要
采用免疫组织化学方法证明：纤维连接素（Ｆｎ）在正常大陆组织中呈现规律性分布，大肠癌癌组织中Ｆｎ的含量减少。经热放化治疗的大肠癌病例，Ｆｎ在癌组织中的基膜、癌细胞间的结缔组织、肿瘤血管、肿瘤周围的结缔组织和肌组织中均明显增为；部分病例的肿瘤周围组织中Ｆｎ形成“带状屏障”。这提示癌细胞退变，淋巴细胞、炎细胞浸润及纤维组织增生与Ｆｎ的分布和含量变化有密切关系。
By immunohistochemical method we have testified that fibronectin has a
regular distribution in the normal large intestine;while inthe colorectal carcinoma,fibronectin
content was less than in the normal tissue.In colorectal carcinoma treated with TRC
fibronectinincreased obviously and its distribution changed. It was shown that distribution and
content of fibronectin was closely related to of thecancer cells degeneratton, inflammatory
infiltration and fibrosis
出处
《第一军医大学学报》
CSCD
1994年第1期18-19,共2页
Journal of First Military Medical University
关键词
纤维连接素
大肠肿瘤
癌
药物疗法
fibronectin,large intestine cancer
thermo-radio-chemotherapy
