摘要
本文比较了冠心病病人(CHD)、非胰岛素依赖型糖尿病病人(NIDD)、NIDD合并CHD病人及正常对照组的血脂、Apo AI、A Ⅱ水平。Logistic回归分析表明,主要是TC的升高与Apo AI水平的降低对冠心病的发生有较密切的关系。与正常对照相比,LDL-C/Apo AI可较其它脂代谢指标更敏感地反映NIDD患者的脂代谢紊乱。无论是血脂,ApoAI、AII还是HbA_2都不能作为区别NIDD与NIDD合并CHD患者的指标。Apo AI、AII与HbA_1、糖尿病病程之间无相关。
The plasma lipids, apolipoprotein AⅠ and AⅡ (apoAⅠ, apoAⅡ) levels were compared among patients with coronary heart disease (CHD), non-insulin dependent diabetics (NIDD) with or without CHD, and weight-age matched controls. The increase in total cholesterol and decrease in apoAⅠ had great influence on the development of CHD by logistic regression analysis. The increase in ratio of LDL-C/apoAⅠ was more sensitive than changes of lipids and apoAⅠ, AⅡ in indicating abnormal lipid metabolism in NIDD. There were no significant difference in HbAl, lipids, and apoAⅠ, AⅡ levels between NIDD with CHD and without CHD by analysis of variance. No correlation was found between apoAⅠ, AⅡ, HbAl, and the course of diabetes.
出处
《上海医学》
CAS
CSCD
北大核心
1989年第3期131-134,共4页
Shanghai Medical Journal
