摘要
报道近10年来我院收治的8例肝性脊髓病患者,占同期肝硬化病人的0.52%(8/1540)。均为男性,平均年龄46岁,有明确肝病史;8例中6例有黄疸、腹水,7例曾有肝昏迷发生。该病临床主要为上运动元损害的表现,主要病理损害为脊髓及大脑白质的脱髓鞘改变,发病机理与肝损害时毒性代谢产物的作用有关,与免疫因素关系不清。在治疗上主要针对原发病。提醒各科医师应注意各系统体征,早期发现及时治疗。
Eight cases of hepatic-myelopathy are reported in recent ten years in our hospital.Accounting for0.52 per cent of the cirrhosis in the same time(8/1543),they are all men and have exactly hepatopathyhistory.6 of 8 cases shows Jaudice and Ascites.Hepatic-encephalophy occured at 7 of 8 cases.Theupper motor-neuron lesion is main clinical manifestation,and the pathologic lesions are demyelinatingof cerebromedullary.The pathogenesis of this sortsof disease may be relative to the toxicant metabolitewhen the hepato-failure occured.The relationshipto immune system is not clear.This paper remindsevery doctors in various departments to pay atten-tion to the signs and symptoms in order to discoverand treat the disease in the early stage.
