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兔胎仔实验性膈疝肺发育不全组织形态学研究——光镜检查肺发育不全的特点

A MORPHOLOGIC STUDY OF PULMONARY HYPOPLASIA IN FETAL RABBITS WITH EXPERIMENTAL DIAPHRAGMATIC HERNIA
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摘要 在兔仔胎龄23~25d行实验性膈疝于29d剖腹取得存活模型8例。同时取19~29d的正常兔胎仔20例。均行光镜检查其肺发育情况。实验性膈疝的肺发育组织形态学显示中央发育较快而周围成熟迟缓。 Experimental diahragmatio hernia was created on fetal rabbits during gestaional day (GD) 23-25d, and 8 rases of the model survived in intrauterin'j life up to the full term -were obtained by hysterotomy for morphologic study on pulmonary hypoplsia. At the samatime 20 normal f^tal rabbits on 19-23d were studied for pulmonary development in scries. Four stages of normal fetal lung development, such as pseudoglandular period (19-23d), canalicular period (23-25d), sacular period (25-28d), and alveolar period (28-23d) were demonstrated. While in the experimental models, the pulmonary development were hindered in various. degrees related to the onset of diaphragmatic hernia on GD, and the extent of compression by herniated intra-abdominal organ
出处 《重庆医科大学学报》 CAS CSCD 1993年第3期188-190,共3页 Journal of Chongqing Medical University
基金 国家自然科学基金
关键词 先天性 膈疝 发育异常 婴儿 Fetal rabbits. Congenital diaphragmatic hernia Pulmonary hypoplasia
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