摘要
本文总结原发性肝癌甲胎蛋白阴性76例,甲胎蛋白阳性281例及误诊为肝癌25例的不同特点,着重讨论甲胎蛋白阴性原发性肝癌的诊断与鉴别诊断问题。结果表明:甲胎蛋白阴性与阳性的原发性肝癌,除了甲胎蛋白外,其它临床资料无统计学意义,仍以上腹胀痛,肝肿块为主要临床症状,有肝炎病史较多,r-GT异常率较高,B超及CT有较高的诊断率。对于有肝炎病史,r-GT异常者,定期B超检查能早期发现肝癌。对于甲胎蛋白阴性的肝内肿块,诊断要慎重,往往难与肝内良性肿瘤,病变鉴别。
Apparently difficulties exist in the diagnosis of primary liver cancer(PLC) when serum alpha feto-protein (AFP) yielded negative result. There were 382 cases which were diagnosed as PLC clinically. Analysis of these cases showed that for the exception of AFP determination there were no significant difference existed between the groups of neg- ative and positive AFP PLC patients. The principal clinical manifestations consisted of upper abdominal pain and palpable mass of the liver. In some of the patients there were history of hepatitis, abnormal serum γ-GT. Sonography and CT scan were of value in making the diagnosis of PLC. For patients who had a history of hepatitis, abnormal γ-GT, despite nega- tive AFP assay monitoring with sonography and CT scan could discover the PLC with ease. Sonography and CT scan of the liver are most helpful in the differential diagnosis when AFP test showed negative result.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1993年第4期265-268,共4页
Chinese Journal of Clinical Oncology
关键词
甲胎蛋白
诊断
肝肿瘤
Aloha feto-protein Primary liver cancer Diagnosis
