摘要
1982年1月至1987年5月收治鼻咽癌292例,均经病理证实为低分化鳞状细胞癌。1、3、5年生存率各为98％(286/292),62％(182/292),46％(134/292)。治疗失败主要原因,仍然是3年内原发灶和颈部淋巴结的复发及远转。本文提示单纯提高放射剂量未能提高生存率。如何提高原发灶的控制率,关键要因人而异,充分利用CT扫描特点,对复发残存病灶行腔内放疗,也可行低氧放疗等措施,对颈部淋巴结采用混合射线及手术切除的综合疗法,积极控制颈动脉鞘区病变是减少运转关键。
From January 1982 to December 1984,169 patients with poor-differentiated squamous cell carcinoma of nasopharynx proved by pathology were treated. The overall 1-,3-,and 5-year survival rates were 98%(286/292), 62%(182/292) and 460%(134/292) respectively. The main causes of failure after radiotherapy were recurrence at the primary site and in cervical lymph nodes or distant metastasis within three years. The authors found that the survival rate can't be increased by escalating radiation dosage alone. It is suggested that with the help of CT scan,combined afterload- ing intracavitary brachytherapy with low oxygen and external irradiation will provide better result and that radiotherapy combined with dissection of involved nodes might improve the outcome. The control of lymph nodes in the carotid sheath region was crucial in minimizing distant metastasis.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1993年第3期188-189,196,共3页
Chinese Journal of Clinical Oncology
关键词
鼻咽肿瘤
放射疗法
Nasopharyngeal carcinoma
Radiotherapy
Enhancement of treatment effect
