摘要
目的：比较硝酸酯类及钙拮抗剂对高压氧诱发脑血栓形成的预防作用。方法：以年龄≥60岁、高血压病、高脂血症、原有脑梗死（或脑出血）、高粘血症和糖尿病为危险因子，将192例行高压氧(HBO)治疗的病人分为3组： ①硝酸酯类组34例；②钙拮抗剂组49例；③未特殊用药组109例，在不同危险因子簇集水平上分析药物的预防作用。结果：簇集3个及3个以下危险因子者无一例发生脑血栓形成，在簇集4个及4个以上危险因子的水平上，硝酸酯类药物有良好的预防作用，而钙拮抗剂组中有33．3%发病，二者有显著性差异(P<0．05)。结论：硝酸酯类药物有显著的预防作用,而钙拮抗剂无此作用。
To compare the preventive effect of cer ebrathrombosis d uring treatment of hyperbaric oxygen between trinitrate and calcium antagoni stMethod：The risk factors: the age of subjects no less than 60, hyperten sion, hyperlipoidemia, remote cerebral thrombosis/hemorrhage, hyperviscosity of blood and diabetes Subjects: 192 patients are subdivided into 3 groups according to administration after treating by HBO Group 1: administer trini trate to patients; group 2: administer calcium antagonist to patients; group3: no administer special medicine to patients To analyze the preventive ef fect on the different levels with various risks factors Results：No patient, who has no more than 3 risk factors, happens cerebral thr ombosis The trinitrate medicines have definitely preventive effect when the risk factors are 4 or more than 4 (0/13), whereas the incidence rate of calcium antagonist group is 33.3% (5/15) It is notable differen t between above two groups (P<0.05)Conclusion：The preventive effect of trinitrate medicine is obviously, whereas calcium an tagonist medicine has no this effect
