摘要
目的 探讨ICU患者院内真菌性败血症的发生特点及其防治策略。方法 收集近 3年来上海长征医院综合性ICU住院患者院内真菌性败血症 5 1例进行回顾性分析。结果 5 1例败血症血微生物培养共获得真菌菌株 5 3株 ,念珠菌是主要病原体 ( 87 14% ) ;入侵途径以中心静脉导管为最多 ( 35 2 9% ) ;总病死率 6 8 6 3% ,为同期ICU病死率的 12 71倍 ;多脏器功能衰竭与感染性休克是预后不良的先兆因素。结论 真菌感染已成为ICU内危重病患者死亡的重要原因。消除易患因素、重视真菌感染的监测。
Objective To study the clinical characteristics, prevention and treatment of nosocomial fungal septicemia.Methods Clinical retrospective study of 51 consecutive patients with nosocomial fungal septicemia.Results 53 fungal strains were isolated from blood. Candida was the predominantly pathogenic organism(87.14%).The most frequent sources of infection were central venous catheters(35.29%).Overall mortality rate was 68.63%.Multi-organ failure and septic shock were the predicting factors of poor prognosis. Conclusions Fungal infection has become prominently fatal cause of critically ill patients. Removing predisposing factors, monitoring fungal pathogen and effective antifunga therapy are important measures to reduce the incidence and mortality of fungal infection. [
出处
《中国急救医学》
CAS
CSCD
北大核心
2001年第2期84-85,共2页
Chinese Journal of Critical Care Medicine
关键词
败血症
真菌
医院感染
重症监护病房
Septicemia
Fungal
Nosocomial infection
Intensive care unit
