摘要
58例慢性肝炎中慢活肝24例、慢迁肝34例，随机接受两种方法治疗，31例口服熊去氧胆酸(UDCA)300mg／d；27例口服维生素类，作对照。治疗6周后，UDCA组血清丙氨酸转氨酶，γ-谷氨酰移换酶明显下降，白蛋白明显上升，而一般治疗组改善不明显；血清碱性磷酸酶无论在UDCA组或一般治疗组中均无明显变化。UDCA治疗未见明显副作用。
The controlled trial was performed in 58 patients with chronic hepatitis (24 active and 34 persistent), randomly assigned to either of the following treatments: ursodeoxycholic acid (UDCA) 300 rag/day(31 patients) and vitamines (27 patients)as control, given for 6 successive weeks. The changes at the end of treatment were more significant in the UDCA group, presenting more decreased serum alanine transaminase (ALT), gamma-glutamyl transferase (GGT), bilirubin and more increased serttm albummin, compared with the control group. The mean serum level of alkaline phosphatase (ALP) changed significantly during neither treatment. The results show that UDCA improves indices of liver injury and it is useful for treatment of patients with chronic hepatitis.
出处
《南通医学院学报》
1989年第4期280-281,344-345,共2页
ACTA Academiae Medicinae Nantong
