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无腺棉仁水提物对实验动物血糖的影响

Effects of water-extract of pigment glandless seed on the levels of blood glucose in experimental animals
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摘要 目的:研究无腺棉仁水提物对实验动物血糖的影响。方法:用四氧嘧啶制备糖尿病大鼠模型,将无腺棉仁水提物给四氧嘧啶型糖尿病大鼠连续灌胃,采血测定不同时间血糖;并观察无腺棉仁水提物单次给药对小鼠糖耐量及肾上腺素型高血糖的影响。结果:无腺棉仁水提物与对照组比较可显著降低四氧嘧啶型糖尿病大鼠血糖(P<0.01),并能对抗糖负荷引起的小鼠血糖升高及对抗肾上腺素引起的生理性高血糖。结论:无腺棉仁水提物对实验动物有降低血糖作用。 Objective: To study the effects of the water-extract of pigment glandless seed on the levels of blood glucose in experimental animals. Methods: Siygangmiding were injected into rats to replicate the model of diabetes, the water-extracts of pigment glandless seed were administered to the rats with diabete caused by siygangmiding through the mouth continously, the levels of blood glucose were detected at different time, the water-extracts of pigment glandless seed were administered to mice only once to determine its effects on the glucose tolerance of the experimental mice and the effects on hyperglycemia caused by adrenaline imbalance. Results: Compared with the controls, the levels of blood glucose of model rats decreased significantly(P<0.01), and the extracts could offer resistance to the increase of blood glucose in the model imce. Conclusion: The water - extracts of pigment glandless seed can reduce the levels of blood glucose in experimental animals.
出处 《河北职工医学院学报》 1999年第2期1-2,共2页 Journal of Hebei Medical College for Continuing Education
基金 河北省科委资助项目 编号:91416411 92216142
关键词 水提物 高血糖 糖尿病大鼠 实验动物 小鼠 影响 糖负荷 灌胃 肾上腺素 采血 Hyperglycemia siyangmiding Glucose tolerance Adrenaline Water - extract of pigment Glandless seed
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  • 1杜玉,解直彬,赵焕蒂,徐景明.藻酸双酯钠临床应用中的不良反应[J]新药与临床,1989(05).
  • 2孟庆棣,许俊杰,林嘉兴.消渴证方对四氧嘧啶型糖尿病兔血糖水平的影响[J]中药通报,1984(06).
  • 3江洪毅,曲鲁平,许心如.藻酸双酯钠治疗糖尿病脂代谢紊乱45例[J].新药与临床,1992,11(1):39-40. 被引量:6

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