摘要
对20名不同状况男性老年人血浆PGI_2、TXA_2、LPO及各类脂蛋白含量进行测定相比较,实验结果表明:老年人血浆中LPO含量与PGI_2/TXA_2比值呈显著负相关(r=-0.681,P<0.01),提示血浆PGI_2/TXA_2比值可能受细胞内LPO的调节,当LPO含量升高可引起内皮细胞的损伤,使PGI_2合成减少。长期坚持长跑锻炼的老年人血浆中PGI_2/TXA_2比值较不参加体育锻炼的对照组明显升高(P<0.05),LPO含量则明显下降(P<0.05),TG、Ch、LDL呈下降趋势,而HDL_2/HDL比值显著升高(P<0.05),提示坚持长期的长跑锻炼可降低体内LPO含量,调整PGI_2/TXA_2比值,并使血浆脂蛋白向更有益于机体健康,对防治老年人动脉粥样硬化等疾病,有效地开展体育活动,提供了依据。
Results of this study showed that the plasma PGI2, TXA, LPO and lipoprotein changed significantly in all aged sub iects after long distanee running. It suggested that health state of the aged might be improved by long distance run,ling. The seientific basis for efficient development of the aged physical activities was discussed.
出处
《中国康复医学杂志》
CAS
CSCD
1993年第3期109-111,共3页
Chinese Journal of Rehabilitation Medicine
关键词
血栓素
过氧化脂质
脂蛋白
长跑
Prostacyclin I_2
Thromboxane A_2
Lipid peroxidation
Lipoprotein
Long distance running