摘要
大鼠气管注入游离SiO_2<3%的粮谷尘100mg后,主要引起小气道炎症并伴有局灶性肉芽肿和轻度的纤维增生现象;但未显示明显的纤维化病变,且注入粮谷尘3个月后病损相对较1个月后轻,考虑其病变具有可逆性。同时染尘组血浆FN量均高于对照组,其含量的变化与病理变化的特点有一定的关系。
Small airway inflammation accompanied by focal granulomatosis and a light increase of fibrosis tissue were shown in the rats injected intratracheally by 100 mg grain dust. However, no obvious fibrosis was shown. In addition, the abnormal changes appeared to be slighter three months exposure than that in one month exposure. Meanwhile, the content of plasma FN was found to be higher in the two exposure groups than the controls. There existed some correlation between the amount of plasma FN and pathological changes. The significance needs further study.
出处
《职业医学》
1993年第1期8-9,共2页
China Occupational Medicine
关键词
粮谷尘
病理
肺损伤
纤维联结蛋白
grain dust, pathology, pulmonary injury, plasma fibronectin
