摘要
目的 探讨多肿瘤抑制基因(p16/MTS1)缺失与骨髓增生异常综合征(MDS)发病的关系。方法 采用PCR技术,对30例MDS的p16/MTS1基因缺失情况进行了分析。结果 30例MDS患者未见有p16基因缺失。结论 提示p16基因缺失和MDS的发病关系不大。
I Objective To investigate the relationship between deletions of multiple tumor suppressor gene-p16/ MTS1 and pathogenesis of MDS. Methods p16 gene was analysed by polymerase chain reaction in 30 MDS patients. Results No p16 gene deletion was found in 30 samples. Conclusion These results indicate the deletion of p16 gene is not associated with pathogenesis of MDS.
出处
《临床输血与检验》
CAS
2000年第3期12-13,共2页
Journal of Clinical Transfusion and Laboratory Medicine
基金
安徽省教委自然科学研究基金
安徽医科大学博士基金