摘要
In this study, we investigated the preventive effects of a probiotic preparation (Miya BM) containing Clostridium butyricum spores against the side effects of Helicobacter pylori eradication. The rats were administered omeprazole, amoxicillin and clarithromycin, which combination of drugs was a new triple-therapy proposed for the firstline therapy by the guideline of the treatment of H.pylori infection in Japan. Obligate anaerobes and Lactobacillus were decreased markedly, while aerobes were increased after the three drugs administration. Moreover, Clostridium difficile causative of antibioticassociated diarrhea was isolated from feces after the 7th. Administration of Miya BM decreased the number of C.difficile in the feces and increased the short chain fatty acids in the intestinal contents.
出处
《胃肠病学》
2000年第B08期116-116,共1页
Chinese Journal of Gastroenterology
