摘要
目的:了解功能性腹痛综合征(functionalabdominalpainsyndrome,FAPS)患者心理健康状况及抗抑郁治疗的效果,探讨提高FAPS患者生活质量的有效干预措施。方法:应用症状自评量表(SCL-90)及汉密顿抑郁量表(HAMD)、汉密顿焦虑量表(HAMA)评定云南省第一人民医院消化科FAPS患者26例,并与21例健康体检者(对照组)进行对照。对其中19例FAPS患者应用盐酸氟西汀20mg/d(批号:031214)治疗8周,疗程结束时用上述量表进行评定,与治疗前进行对比。结果:研究组治疗前SCL-90、HAMD、HAMA量表评分除精神病性外,其余各项与对照组比较,差异均有显著性(P<0.01);治疗后除惊恐及日夜变化外,其余各项与治疗前比较,差异均有显著性(P<0.01)。结论:FAPS患者普遍存在抑郁焦虑等不良情绪,抗抑郁治疗能改善抑郁焦虑症状。
AIM:To apprehend the mental health status of patients with functional abdominal pain syndrome(FAPS) and the effect of antidepressant treatment,so as to provide effective interventions for the improvement of quality of life(QOL) of the FAPS patients. METHODS:Twenty six FAPS patients,who were hospitalized in the Department of Gastroenterology,Kunming Provincial First People's Hospital,and 21 healthy physical examinees(control group) were assessed with symptom checklist 90(SCL 90),Hamilton rating scale for depression(HAMD) and Hamilton rating scale for anxiety(HAMA).Nineteen cases of the FAPS patients were treated with fluoxertine hydrochloride(batch number: 031214) 20 mg per day for 8 weeks,and they were evaluated with the above scales at the end of treatment,and the results were compared with those before treatment. RESULTS:Before treatment,there were significant differences in the total scores and each factor scores in SCL 90,HAND and HAMA between the study group and control group except the score of psychosis(P< 0.01). After treatment,the scores of all the items were significantly different from those before treatment except for the scores of panic and diurnal variation(P< 0.01). CONCLUSION:FAPS patients are usually accompanied with bad emotions,such as depression or anxiety,which can be ameliorated by antidepressant therapy.
出处
《中国临床康复》
CSCD
北大核心
2005年第8期18-19,共2页
Chinese Journal of Clinical Rehabilitation
